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020 |a9781315657967|q(electronic bk.)
020 |a1315657961|q(electronic bk.)
020 |a9781317329633|q(electronic bk. : PDF)
020 |a1317329635|q(electronic bk. : PDF)
020 |a9781317329626|q(electronic bk. : EPUB)
020 |a1317329627|q(electronic bk. : EPUB)
020 |a9781317329619|q(electronic bk. : Mobipocket)
020 |a1317329619|q(electronic bk. : Mobipocket)
020 |z9781138999985
020 |z1138999989
035 |a(OCoLC)1085890953
035 |a(OCoLC-P)1085890953
040 |aOCoLC-P|beng|erda|epn|cOCoLC-P
041 |aeng
049 |aTürk Tarih Kurumu Kütüphanesi
050 4|aRC455.4.G4|bA77 2019eb
072 7|aHEA|x039000|2bisacsh
072 7|aMED|x014000|2bisacsh
072 7|aMED|x022000|2bisacsh
072 7|aMED|x112000|2bisacsh
072 7|aMED|x045000|2bisacsh
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072 7|aJHB|2bicssc
082 04|a616.89/042|223
100 1 |aArribas-Ayllon, Michael,|eauthor.
245 10|aPsychiatric genetics :|bfrom hereditary madness to big biology /|cMichael Arribas-Ayllon, Andrew Bartlett and Jamie Lewis.
264 1|aMilton Park, Abingdon, Oxon ;|aNew York, NY :|bRoutledge,|c2019.
300 |a1 online resource.
336 |atext|btxt|2rdacontent
337 |acomputer|bc|2rdamedia
338 |aonline resource|bcr|2rdacarrier
505 0 |aCover; Half Title; Series Page; Title Page; Copyright Page; Table of Contents; List of Tables; Acknowledgements; Introduction; Entering 'Big Biology'; Psychiatric genetics as 'Big Biology'; Styles of reasoning; Networks of production; Argument and methods; Notes; References; Chapter 1: From 'hereditary madness' to psychiatric genetics; Early modern discourse on hereditary; The constitution of heredity; Hereditarian psychiatry; Science of heredity; Mendelian statistics; Conclusion; Notes; References; Chapter 2: The birth of psychiatric genetics; A new statement on method; Tracing a network
505 8 |aA new nosologyThe genealogical turn; The Munich School; Rüdin's legacy; Twin studies; Dialectics of twin and adoption studies; Theoretical imagination of schizophrenia; Conclusion; Notes; References; Chapter 3: The rhetoric of complexity; Failure of linkage studies; Rhetoric in scientific writing; Accounting for complexity; Retrospective accounting; Prospective accounting; Rebuilding the narrative; Conclusion; Note; References; Chapter 4: Inside 'Big Biology'; Large-scale biology; Inside the Centre; Consortium-based collaboration; Genotyping and outsourcing; Doing biology?; Conclusion; Notes
505 8 |aScientists' accounts of publics and engagementCinderella science; Analogies to disease; Conclusion; Notes; References; Chapter 8: Big Biology then and now: The trouble with GWAS; Don't give up on GWAS; Where do we go from here?; What's in a letter?; Inside the 'Death Star'; Consortium-based collaboration; Doing biology; Large-scale phenotyping; Mobility and immobility; Identity; Conclusion; Notes; References; Conclusion: Big Biology and scientific revolutions; References; Index
520 |aPsychiatric genetics has become 'Big Biology'. This may come as a surprising development to those familiar with its controversial history. From eugenic origins and contentious twin studies to a global network of laboratories employing high-throughput genetic and genomic technologies, biological research on psychiatric disorders has become an international, multidisciplinary assemblage of massive data resources. How did psychiatric genetics achieve this scale? How is it socially and epistemically organized? And how do scientists experience this politics of scale? Psychiatric Genetics: From Hereditary Madness to Big Biology develops a sociological approach of exploring the origins of psychiatric genetics by tracing several distinct styles of scientific reasoning that coalesced at the beginning of the twentieth century. These styles of reasoning reveal, among other things, a range of practices that maintain an extraordinary stability in the face of radical criticism, internal tensions and scientific disappointments. The book draws on a variety of methods and materials to explore these claims. Combining genealogical analysis of historical literature, rhetorical analysis of scientific review articles, interviews with scientists, ethnographic observations of laboratory practices and international conferences, this book offers a comprehensive and detailed exploration of both local and global changes in the field of psychiatric genetics.
588 |aOCLC-licensed vendor bibliographic record.
650 0|aMental illness|xGenetic aspects.
650 0|aBehavior genetics.
650 7|aHEALTH & FITNESS / Diseases / General|2bisacsh
650 7|aMEDICAL / Clinical Medicine|2bisacsh
650 7|aMEDICAL / Diseases|2bisacsh
650 7|aMEDICAL / Evidence-Based Medicine|2bisacsh
650 7|aMEDICAL / Internal Medicine|2bisacsh
650 7|aSOCIAL SCIENCE / General|2bisacsh
650 7|aSOCIAL SCIENCE / Sociology / General|2bisacsh
700 1 |aBartlett, Andrew|q(Andrew James),|d1977-|eauthor.
700 1 |aLewis, Jamie,|d1979-|eauthor.
856 40|3Taylor & Francis|uhttps://www.taylorfrancis.com/books/9781315657967
856 42|3OCLC metadata license agreement|uhttp://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf
901 |aTaylor & Francis